综合产生的内容的广泛扩散是一种需要紧急对策的严重威胁。合成含量的产生不限于多媒体数据，如视频，照片或音频序列，但涵盖了可以包括生物图像的显着大面积，例如西幕和微观图像。在本文中，我们专注于检测综合生成的西幕图像。生物医学文献在很大程度上探讨了西部污染图像，已经表明了如何通过目视检查或标准取证检测器轻松地伪造这些图像。为了克服缺乏公开可用的数据集，我们创建了一个包含超过14k原始的西幕图像和18K合成的Western-Blot图像的新数据集，由三种不同的最先进的生成方法产生。然后，我们调查不同的策略来检测合成的Western印迹，探索二进制分类方法以及单级探测器。在这两种情况下，我们从不利用培训阶段的合成纤维图像。所达到的结果表明，即使在这些科学图像的合成版本未优化利用检测器，综合生成的西幕图像也可以具有良好的精度。

这项工作使用来自建设性模拟的可靠数据比较了监督的机器学习方法，以估算空袭期间发射导弹的最有效时刻。我们采用了重采样技术来改善预测模型，分析准确性，精度，召回和F1得分。的确，我们可以根据决策树以及其他算法对重采样技术的显着敏感性来确定模型的显着性能。最佳F1分数的模型的值分别为0.379和0.465，而没有重新采样技术，这一值分别增加了22.69％。因此，如果理想，重新采样技术可以改善模型的召回率和F1得分，而准确性和精确度略有下降。因此，通过通过建设性模拟获得的数据，可以根据机器学习模型开发决策支持工具，从而可以提高BVR空中战斗的飞行质量，从而提高进攻任务的有效性以达到特定目标。

深度学习体系结构已在不同领域（例如医学，农业和安全）取得了有希望的结果。但是，由于培训过程中所需的大型收藏品，在许多实际应用中使用这些强大的技术变得具有挑战性。几项作品通过提出可以更少学习更多知识的策略，例如弱和半监督的学习方法来克服它来克服它。由于这些方法通常无法解决对对抗性例子的记忆和敏感性，因此本文介绍了三种深度度量学习方法与混音相结合，以实现不完整的监督场景。我们表明，在这种情况下，指标学习中的一些最新方法可能无法很好地工作。此外，所提出的方法在不同数据集中的表现优于大多数。

这项工作调查了使用深神经网络（DNN）来执行武器接触区域（WEZ）最大发射范围的估计。韦茨允许飞行员识别空域，其中可用导弹具有更大的成功参与特定目标的概率，即围绕着对手易受射击群体的飞机的假设区域。我们提出了一种方法来确定使用50,000个变化条件下的模拟发射的给定导弹的韦茨。这些模拟用于训练当飞机在不同的烧制条件下发现自身时，可以预测韦茨的DNN，其测定系数为0.99。它提供了另一种关于前面研究的程序，因为它采用了非离散化模型，即，它立即考虑了WEZ的所有方向，以前尚未完成。此外，所提出的方法使用实验设计，允许较少的模拟运行，提供更快的模型训练。

这项工作旨在在防御柜台（DCA）任务的背景下提供超出视觉范围（BVR）空战的参与决策支持工具。在BVR AIR作战中，接合判决是指通过假设令人反感的姿态和执行相应的演示来选择导频的时刻。为了模拟这一决定，我们使用巴西空军航空航天仿真环境（\ {Ambiente de Simula \ C {C} \〜a \〜a \〜ao ao aeroispacial - Asa}在葡萄牙语中，它产生了3,729个建设性模拟，每个建设性模拟持续12分钟，总共10,316场比赛。我们通过称为DCA指数的操作性标准分析了所有样本，这些标准基于主题专家的经验，这类使命的成功程度代表。该公制考虑了同一团队和对方团队的飞机的距离，对抗空气巡逻的点以及所使用的导弹数。通过在整个参与过程中开始和DCA指数的平均值之前定义参与状态，我们创建了一个监督的学习模型，以确定新的参与的质量。一种基于决策树的算法，与XGBoost库一起使用，提供了一种回归模型，以预测具有接近0.8的确定系数的DCA索引和0.05的根均方误差，可以为BVR飞行员提供参数以决定是否或不要搞。因此，使用通过仿真获得的数据，这项工作通过基于BVR Air战斗的机器学习构建决策支持系统而有贡献。

Accurate determination of a small molecule candidate (ligand) binding pose in its target protein pocket is important for computer-aided drug discovery. Typical rigid-body docking methods ignore the pocket flexibility of protein, while the more accurate pose generation using molecular dynamics is hindered by slow protein dynamics. We develop a tiered tensor transform (3T) algorithm to rapidly generate diverse protein-ligand complex conformations for both pose and affinity estimation in drug screening, requiring neither machine learning training nor lengthy dynamics computation, while maintaining both coarse-grain-like coordinated protein dynamics and atomistic-level details of the complex pocket. The 3T conformation structures we generate are closer to experimental co-crystal structures than those generated by docking software, and more importantly achieve significantly higher accuracy in active ligand classification than traditional ensemble docking using hundreds of experimental protein conformations. 3T structure transformation is decoupled from the system physics, making future usage in other computational scientific domains possible.

Variational autoencoders model high-dimensional data by positing low-dimensional latent variables that are mapped through a flexible distribution parametrized by a neural network. Unfortunately, variational autoencoders often suffer from posterior collapse: the posterior of the latent variables is equal to its prior, rendering the variational autoencoder useless as a means to produce meaningful representations. Existing approaches to posterior collapse often attribute it to the use of neural networks or optimization issues due to variational approximation. In this paper, we consider posterior collapse as a problem of latent variable non-identifiability. We prove that the posterior collapses if and only if the latent variables are non-identifiable in the generative model. This fact implies that posterior collapse is not a phenomenon specific to the use of flexible distributions or approximate inference. Rather, it can occur in classical probabilistic models even with exact inference, which we also demonstrate. Based on these results, we propose a class of latent-identifiable variational autoencoders, deep generative models which enforce identifiability without sacrificing flexibility. This model class resolves the problem of latent variable non-identifiability by leveraging bijective Brenier maps and parameterizing them with input convex neural networks, without special variational inference objectives or optimization tricks. Across synthetic and real datasets, latent-identifiable variational autoencoders outperform existing methods in mitigating posterior collapse and providing meaningful representations of the data.

Differentiable Architecture Search (DARTS) has attracted considerable attention as a gradient-based Neural Architecture Search (NAS) method. Since the introduction of DARTS, there has been little work done on adapting the action space based on state-of-art architecture design principles for CNNs. In this work, we aim to address this gap by incrementally augmenting the DARTS search space with micro-design changes inspired by ConvNeXt and studying the trade-off between accuracy, evaluation layer count, and computational cost. To this end, we introduce the Pseudo-Inverted Bottleneck conv block intending to reduce the computational footprint of the inverted bottleneck block proposed in ConvNeXt. Our proposed architecture is much less sensitive to evaluation layer count and outperforms a DARTS network with similar size significantly, at layer counts as small as 2. Furthermore, with less layers, not only does it achieve higher accuracy with lower GMACs and parameter count, GradCAM comparisons show that our network is able to better detect distinctive features of target objects compared to DARTS.

Deep learning techniques with neural networks have been used effectively in computational fluid dynamics (CFD) to obtain solutions to nonlinear differential equations. This paper presents a physics-informed neural network (PINN) approach to solve the Blasius function. This method eliminates the process of changing the non-linear differential equation to an initial value problem. Also, it tackles the convergence issue arising in the conventional series solution. It is seen that this method produces results that are at par with the numerical and conventional methods. The solution is extended to the negative axis to show that PINNs capture the singularity of the function at $\eta=-5.69$

The Government of Kerala had increased the frequency of supply of free food kits owing to the pandemic, however, these items were static and not indicative of the personal preferences of the consumers. This paper conducts a comparative analysis of various clustering techniques on a scaled-down version of a real-world dataset obtained through a conjoint analysis-based survey. Clustering carried out by centroid-based methods such as k means is analyzed and the results are plotted along with SVD, and finally, a conclusion is reached as to which among the two is better. Once the clusters have been formulated, commodities are also decided upon for each cluster. Also, clustering is further enhanced by reassignment, based on a specific cluster loss threshold. Thus, the most efficacious clustering technique for designing a food kit tailored to the needs of individuals is finally obtained.